For English, see below The reproduction number R gives the average number of people infected by one person with COVID-19. To estimate this reproduction number, we use the number of reported COVID-19 hospital admissions per day in the Netherlands. This number of hospital admissions is tracked by the NICE Foundation (National Intensive Care Evaluation). Because a COVID-19 admission is passed on with some delay in the reporting system, we correct the number of admissions for this delay [1]. The first day of illness is known for a large proportion of the reported cases. This information is used to estimate the first day of illness for hospital admissions. By displaying the number of COVID-19 admissions per date of the first day of illness, it is immediately possible to see whether the number of infections is increasing, peaking or decreasing. For the calculation of the reproduction number, it is also necessary to know the length of time between the first day of illness of a COVID-19 case and the first day of illness of his or her infector. This duration is an average of 4 days for SARS-CoV-2 variants in 2020 and 2021, and an average of 3.5 days for more recent variants, calculated on the basis of COVID-19 reports to the GGD. With this information, the value of the reproduction number is calculated as described in Wallinga & Lipsitch 2007 [2]. Until June 12, 2020, the reproduction number was calculated on the basis of COVID-19 hospital admissions, and until March 15, 2023, the reproduction number was calculated on the basis of COVID-19 reports to the GGDs. [1] van de Kassteele J, Eilers PHC, Wallinga J. Nowcasting the Number of New Symptomatic Cases During Infectious Disease Outbreaks Using Constrained P-spline Smoothing. Epidemiology. 2019;30(5):737-745. doi:10.1097/EDE.0000000000001050. [2] Wallinga J, Lipsitch M. How generation intervals shape the relationship between growth rates and reproductive numbers. Proc Biol Sci. 2007;274(1609):599-604. doi:10.1098/rspb.2006.3754. Description of the variables: Version: Version number of the dataset. When the content of the dataset is structurally changed (so not the daily update or a correction at record level), the version number will be adjusted (+1) and also the corresponding metadata in RIVMdata (https://data.rivm.nl) . Version 2 update (February 8, 2022): - In the calculation of the reproduction number, the date of the positive test result is now used instead of the GGD notification date. Version 3 update (February 17, 2022): - The calculation of the reproduction number now takes into account different generation times for different variants. For the variants up to and including Delta, the average generation time is 4 days, from Omikron it is 3.5 days. The reproduction number published here is a weighted average of the reproduction numbers per variant. Version 4 update (September 1, 2022): - From September 1, 2022, this dataset is split into two parts. The first part contains the dates from the start of the pandemic to October 3, 2021 (week 39) and contains "tm" in the file name. This data will no longer be updated. The second part contains the data from October 4, 2021 (week 40) and is updated every Tuesday and Friday. - Until August 31, the published reproduction number was calculated with the data of the day before publication. From September 1, the published reproduction number is calculated with the data of the day of publication. Version 5 update (March 31, 2023): - From March 15, 2023, the reproduction number is calculated based on COVID-19 hospital admissions according to the NICE hospital registration. From June 13, 2020 to March 14, 2023, the reproduction number was calculated on the basis of COVID-19 reports to the GGD. However, the number of reports is strongly determined by the test policy, and is less suitable as a basis for calculating the reproduction number due to the adjusted test policy as of March 10, 2023 and the closure of the GGD test lanes as of March 17, 2023. Until 12 June 2020, the reproduction number was also calculated on the basis of hospital admissions, but then as reported to the GGD. Date: Date for which the reproduction number was estimated Rt_low: Lower bound 95% confidence interval Rt_avg: Estimated reproduction number Rt_up: Upper bound 95% confidence interval population: patient population with value “hosp” for hospitalized patients or “testpos” for test positive patients For recent R estimates, the reliability is not great, because the reliability depends on the time between infection and becoming ill and the time between becoming ill and reporting. Therefore, the variable Rt_avg is absent in the last two weeks. -------------------------------------------------- --------------------------------------------- Covid-19 reproduction number The reproduction number R gives the average number of people infected by one person with COVID-19. To estimate this reproduction number, we use the number of reported COVID-19 hospital admissions per day in the Netherlands. This number of hospital admissions is tracked by the NICE Foundation (National Intensive Care Evaluation). Because a COVID-19 admission is reported with some delay in the reporting system, we correct the number of admissions for this delay [1]. The first day of illness is known for a large proportion of the reported cases. This information is used to estimate the first day of illness for hospital admissions. By displaying the number of COVID-19 admissions per date of the first day of illness, it is immediately possible to see whether the number of infections is increasing, peaking or decreasing. To calculate the reproduction number, it is also necessary to know the length of time between the first day of illness of a COVID-19 case and the first day of illness of his or her infector. This duration is an average of 4 days for SARS-CoV-2 variants in 2020 and 2021, and an average of 3.5 days for more recent variants, calculated on the basis of COVID-19 reports to the PHS. With this information, the value of the reproduction number is calculated as described in Wallinga & Lipsitch 2007 [2]. Until June 12, 2020, the reproduction number was calculated on the basis of COVID-19 hospital admissions, and until March 15, 2023, the reproduction number was calculated on the basis of COVID-19 reports to the GGDs. [1] van de Kassteele J, Eilers PHC, Wallinga J. Nowcasting the Number of New Symptomatic Cases During Infectious Disease Outbreaks Using Constrained P-spline Smoothing. Epidemiology. 2019;30(5):737-745. doi:10.1097/EDE.0000000000001050. [2] Wallinga J, Lipsitch M. How generation intervals shape the relationship between growth rates and reproductive numbers. Proc Biol Sci. 2007;274(1609):599-604. doi:10.1098/rspb.2006.3754. Description of the variables: Version: Version number of the dataset. When the content of the dataset is structurally changed (so not the daily update or a correction at record level), the version number will be adjusted (+1) and also the corresponding metadata in RIVMdata (https://data.rivm.nl). Version 2 update (February 8, 2022): - In the calculation of the reproduction number, the date of the positive test result is now used instead of the PHS notification date. Version 3 update (February 17, 2022): - The calculation of the reproduction number now takes into account different generation times for different variants. For the variants up to and including Delta, the average generation time is 4 days, from Omikron it is 3.5 days. The reproduction number published here is a weighted average of the reproduction numbers per variant. Version 4 update (September 1, 2022): - As of September 1, 2022, this dataset is split into two parts. The first part contains the dates from the start of the pandemic till October 3, 2021 (week 39) and contains "tm" in the file name. This data will no longer be updated. The second part contains the data from October 4, 2021 (week 40) and is updated every Tuesday and Friday. - Until August 31, the published reproduction number was calculated with the data of the day before publication. From September 1, the published reproduction number is calculated with the data of the day of publication. Version 5 update (March 31, 2023): - As of March 15, 2023, the reproduction number is calculated based on COVID-19 hospital admissions according to the NICE hospital registry. From June 13, 2020 to March 14, 2023, the reproduction number was calculated on the basis of COVID-19 reports to the PHS. However, the number of reports is strongly determined by the test policy, and is less suitable as a basis for calculating the reproduction number due to the adjusted test policy as of March 10, 2023 and the closure of the PHS test lanes as of March 17, 2023. Until 12 June 2020, the reproduction number was also calculated on the basis of hospital admissions, but then as reported to the PHS. Date: Date for which the reproduction number was estimated Rt_low: Lower limit 95% confidence interval Rt_avg: Estimated reproduction number Rt_up: Upper bound 95% confidence interval population: patient population with value “hosp” for hospitalized patients or “testpos” for test positive patients For recent R estimates, the reliability is not great, because the reliability depends on the time between infection and becoming ill and the time between becoming ill and reporting. Therefore, the variable Rt_avg is absent in the last two weeks.